It's been a while, but here goes...

The Separatist Movement

Their leadership, under the guidance of characters such as Nute Gunray, and the heads of the Corporate Alliance, the Banking Clan and the Techno Union, threw its weight behind Darth Sideous' efforts to overthrow the Republic and replace it with a better, more unified organisation. In that respect they were unified and solid - fighting for the right to separate from the corrupt and crumbling Republic and start afresh under new, strong leadership. Headed by the fallen Jedi Knight Count Dooku, the Separatist movement, while enemies of the Republic, had an agenda and a mission statement, and at the end of the Clone Wars prepared for victory, wealth and power.

But Darth Sideous had other, long-term ideas. He had Anakin Skywalker distabilise the Separatist movement by killing Dooku in cold blood and replacing him with General Grievous. Upon the Generals death they were sent to safety on the world of Mustafar. But after Order 66 and the disabling of all Battle Droids across the galaxy he sent his new apprentice Darth Vader to Mustafar to execute the Separatist Council.
The galaxy believed the Jedi, already largely mistrusted by the public, had turned on the Republic, and Palpatine used 'his Clone Army' to end that threat, and instituted a new Empire, to protect the galaxy.

In a stroke Mustafar effectively played host to both the end of the Jedi Order and the Separatist Movement.

But...

While the top tier leadership of the Separatist Movement were privy to knowledge and information that lower ranking officials were not, would the surviving members of each individual arm of the movement - Trade Federation, Corporate Alliance, Banking Clan and Techno Union - follow the same ideals?
Isn't it possible that these new leaders, suddenly finding themselves ousted from potential power by The Emperor and this new Empire, would follow their Separatist ideals. Break away from the leadership and start...a Rebellion?

Isn't it possible that the ashes of the Separatist Movement could have helped give rise to the Rebellion?